Healthcare exposures and associated risk of endocarditis after open-heart cardiac valve surgery.

ABSTRACT:

Background

Infective endocarditis (IE) following cardiac valve surgery is associated with high morbidity and mortality. Data on the impact of iatrogenic healthcare exposures on this risk are sparse. This study aimed to investigate risk factors including healthcare exposures for post open-heart cardiac valve surgery endocarditis (PVE).

Methods

In this population-linkage cohort study, 23,720 patients who had their first cardiac valve surgery between 2001 and 2017 were identified from an Australian state-wide hospital-admission database and followed-up to 31 December 2018. Risk factors for PVE were identified from multivariable Cox regression analysis and verified using a case-crossover design sensitivity analysis.

Results

In 23,720 study participants (median age 73, 63%

SUBMITTER: Kwan TN 

PROVIDER: S-EPMC10854101 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature