Proteomics Analysis of Pregnancy in Ewes under Heat Stress Conditions and Melatonin Administration.

ABSTRACT: Melatonin is an indoleamine with broad spectrum properties that acts as a regulator of antioxidant and immune response in organisms. In our previous studies, melatonin improved redox status and inflammatory response in pregnant ewes under heat stress conditions. In the present study, using proteomics, the proteins regulated by melatonin during different stages of pregnancy and lambing were assessed. Twenty-two ewes equally divided into two groups, the melatonin (M) (n = 11) and control (C) group (n = 11), participated in the study and were exposed to heat stress during the first months of pregnancy. In the M group, melatonin implants were administered throughout pregnancy, every 40 days, until parturition (a total of four implants per ewe). Blood samples were collected at the beginning of

SUBMITTER: Bouroutzika E 

PROVIDER: S-EPMC10854642 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature