Annurca Apple Oleolite as Functional Ingredient for the Formulation of Cosmetics with Skin-Antiaging Activity.

ABSTRACT: The identification of natural remedies for the management of the skin aging process is an increasingly growing issue. In this context, ursolic acid (UA), a ubiquitous molecule, mainly contained in Annurca apple (AA) fruit, has demonstrated valuable cosmetic potential. To this end, in the current study, the AA oleolite (AAO, extract in sunflower oil containing 784.40 ± 7.579 µg/mL of UA) was evaluated to inhibit porcine elastase enzymatic reactions through a validated spectrophotometric method. AAO has shown a valuable capacity to contrast the elastase enzyme with a calculated IC₅₀ of 212.76 mg/mL, in comparison to UA (IC₅₀ of 135.24 μg/mL) pure molecules and quercetin (IC₅₀ of 72.47 μg/mL) which are used as positive controls. In this context and in view of

SUBMITTER: Di Lorenzo R 

PROVIDER: S-EPMC10855134 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature