Somatic Mutations in Latin American Breast Cancer Patients: A Systematic Review and Meta-Analysis.

ABSTRACT: (1) Background: Somatic mutations may be connected to the exposome, potentially playing a role in breast cancer's development and clinical outcomes. There needs to be information regarding Latin American women specifically, as they are underrepresented in clinical trials and have limited access to somatic analysis in their countries. This study aims to systematically investigate somatic mutations in breast cancer patients from Latin America to gain a better understanding of tumor biology in the region. (2) Methods: We realize a systematic review of studies on breast cancer in 21 Latin American countries using various databases such as PubMed, Google Scholar, Web of Science, RedAlyc, Dianlet, and Biblioteca Virtual en Salud. Of 392 articles that fit the criteria, 10 studies have clinical da

SUBMITTER: Martinez-Nava GA 

PROVIDER: S-EPMC10855727 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature