Quantitative Analysis of Hair Luster in a Novel Ultraviolet-Irradiated Mouse Model.

ABSTRACT: Hair luster is a key attribute of healthy hair and a crucial aspect of cosmetic appeal, reflecting the overall health and vitality of hair. Despite its significance, the advancement of therapeutic strategies for hair luster enhancement have been limited due to the absence of an effective experimental model. This study aimed to establish a novel animal model to assess hair gloss, employing ultraviolet (UV) irradiation on C57BL/6 mice. Specifically, UVB irradiation was meticulously applied to the shaved skin of these mice, simulating conditions that typically lead to hair luster loss in humans. The regrowth and characteristics of the hair were evaluated using a dual approach: an Investigator's Global Assessment (IGA) scale for subjective assessment and an image-based pixel-count method for o

SUBMITTER: Chung KB 

PROVIDER: S-EPMC10855743 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature