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Unveiling the Antiviral Efficacy of Forskolin: A Multifaceted In Vitro and In Silico Approach.


ABSTRACT: Coleus forskohlii (Willd.) Briq. is a medicinal herb of the Lamiaceae family. It is native to India and widely present in the tropical and sub-tropical regions of Egypt, China, Ethiopia, and Pakistan. The roots of C. forskohlii are edible, rich with pharmaceutically bioactive compounds, and traditionally reported to treat a variety of diseases, including inflammation, respiratory disorders, obesity, and viral ailments. Notably, the emergence of viral diseases is expected to quickly spread; consequently, these data impose a need for various approaches to develop broad active therapeutics for utilization in the management of future viral infectious outbreaks. In this study, the naturally occurring labdane diterpenoid derivative, Forskolin, was obtained from Coleus forskohlii

SUBMITTER: Amen Y 

PROVIDER: S-EPMC10856047 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature