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A Data-Driven Framework for Clinical Decision Support Systems in Positive Airway Pressure and Oxygen Titration.


ABSTRACT:

Background

Current obstructive sleep apnea treatment relies on manual PAP titration, but it has limitations. Complex interactions during titration and variations in SpO2 data accuracy pose challenges. Patients with co-occurring chronic hypercapnia may require precise oxygen titration. To address these issues, we propose a Clinical Decision Support System using Markov decision processes.

Methods

This study, compliant with data protection laws, focused on adults with OSA-induced hypoxemia utilizing supplemental oxygen and CPAP/BiPAP therapy. PAP titration, conducted over one night, involved vigilant monitoring of vital signs and physiological parameters. Adjustments to CPAP pressure, potential BiLevel transitions, and supplemental oxygen were precisely guided by pat

SUBMITTER: Svaza A 

PROVIDER: S-EPMC10856483 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature