Characterization of the Increase in Narcolepsy following the 2009 H1N1 Pandemic in Sweden.

ABSTRACT: (1) Background: In the context of the H1N1 pandemic and the Pandemrix vaccination campaign, an increased number of narcolepsy cases were noted in several countries. In Sweden, this phenomenon was attributed to the effect of the Pandemrix vaccination in the first place. Studies from China indicated that narcolepsy could occur as a consequence of the H1N1 infection itself. We performed an analysis of the increase, with a specific interest in age and sex distribution. We also aimed to validate the origin of the excess cases, post hoc. (2) Methods: Data for narcolepsy patients (ICD code G 47.4, both type 1 and type 2) distributed by sex and age at 5-year intervals, annually between 2005 and 2017, were retrieved from the National Patient Register. Information on the total population was collect

SUBMITTER: Gauffin H 

PROVIDER: S-EPMC10856509 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature