Upconversion-Powered Photoelectrochemical Bioanalysis for DNA Sensing.

ABSTRACT: In this work, we report a new concept of upconversion-powered photoelectrochemical (PEC) bioanalysis. The proof-of-concept involves a PEC bionanosystem comprising a NaYF₄:Yb,Tm@NaYF₄ upconversion nanoparticles (UCNPs) reporter, which is confined by DNA hybridization on a CdS quantum dots (QDs)/indium tin oxide (ITO) photoelectrode. The CdS QD-modified ITO electrode was powered by upconversion absorption together with energy transfer effect through UCNPs for a stable photocurrent generation. By measuring the photocurrent change, the target DNA could be detected in a specific and sensitive way with a wide linear range from 10 pM to 1 μM and a low detection limit of 0.1 pM. This work exploited the use of UCNPs as signal reporters and realized upconversion-powered PEC bio

SUBMITTER: Liu H 

PROVIDER: S-EPMC10856881 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature