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Fetal loss and long-term maternal morbidity and mortality: A systematic review and meta-analysis.


ABSTRACT:

Background

Evidence suggests common pathways between pregnancy losses and subsequent long-term maternal morbidity, rendering pregnancy complications an early chronic disease marker. There is a plethora of studies exploring associations between miscarriage and stillbirth with long-term adverse maternal health; however, these data are inconclusive.

Methods and findings

We systematically searched MEDLINE, EMBASE, AMED, BNI, CINAHL, and the Cochrane Library with relevant keywords and MeSH terms from inception to June 2023 (no language restrictions). We included studies exploring associations between stillbirth or miscarriage and incidence of cardiovascular, malignancy, mental health, other morbidities, and all-cause mortality in women without previous pregnancy loss. Studies rep

SUBMITTER: Vlachou F 

PROVIDER: S-EPMC10857720 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature