Envelope following response measurements in young veterans are consistent with noise-induced cochlear synaptopathy.

ABSTRACT: Animal studies have demonstrated that noise exposure can lead to the loss of the synapses between the inner hair cells and their afferent auditory nerve fiber targets without impacting auditory thresholds. Although several non-invasive physiological measures appear to be sensitive to cochlear synaptopathy in animal models, including auditory brainstem response (ABR) wave I amplitude, the envelope following response (EFR), and the middle ear muscle reflex (MEMR), human studies of these measures in samples that are expected to vary in terms of the degree of noise-induced synaptopathy have resulted in mixed findings. One possible explanation for the differing results is that synaptopathy risk is lower for recreational noise exposure than for occupational or military noise exposure. The goal o

SUBMITTER: Bramhall NF 

PROVIDER: S-EPMC10857793 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature