Microstructure of the silk fibroin-based hydrogel scaffolds derived from the orb-web spider Trichonephila clavata.

ABSTRACT: Due to the unique properties of the silk fibroin (SF) made from silkworm, SF-based hydrogels have recently received significant attention for various biomedical applications. However, research on the SF-based hydrogels isolated from spider silks has been rtricted due to the limited collection and preparation of naïve silk materials. Therefore, this study focused on the microstructural characteristics of hydrogel scaffolds derived from two types of woven silk glands: the major ampullate gland (MAG) and the tubuliform gland (TG), in the orb-web spider Trichonephila clavate. We compared these spider glands with those of the silk fibroin (SF) hydrogel scaffold extracted from the cocoon of the insect silkworm Bombyx mori. Our FESEM analysis revealed that the SF hydrogel has high porosity, trans

SUBMITTER: Sun Y 

PROVIDER: S-EPMC10858014 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature