Global, regional, and national burdens of cirrhosis in children and adolescents aged under 19 years from 1990 to 2019.

ABSTRACT:

Background & aims

Cirrhosis was the leading cause of morbidity and mortality in adults, but data on the burden and trends were sparse in children and adolescents. We aimed to assess the trends in 204 countries and territories over the past 30 years in children and adolescents aged 0-19 years.

Methods

Data on cirrhosis was collected by the Global Burden of Disease (GBD) 2019 database from 1990 to 2019. We reported on the number, rates, and average annual percentage changes (AAPCs) of incidence and disability-adjusted life-years (DALYs) of cirrhosis at global, regional, and national level.

Results

Globally, the incident numbers of cirrhosis in children and adolescents increased from 204,767 in 1990 to 241,364 in 2019, an increase of 17.9%, with an AAPC 0.13(0.10 to 0.16

SUBMITTER: Zhang C 

PROVIDER: S-EPMC10858162 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature