Grid-like entorhinal representation of an abstract value space during prospective decision making.

ABSTRACT: How valuable a choice option is often changes over time, making the prediction of value changes an important challenge for decision making. Prior studies identified a cognitive map in the hippocampal-entorhinal system that encodes relationships between states and enables prediction of future states, but does not inherently convey value during prospective decision making. In this fMRI study, participants predicted changing values of choice options in a sequence, forming a trajectory through an abstract two-dimensional value space. During this task, the entorhinal cortex exhibited a grid-like representation with an orientation aligned to the axis through the value space most informative for choices. A network of brain regions, including ventromedial prefrontal cortex, tracked the prospective

SUBMITTER: Nitsch A 

PROVIDER: S-EPMC10858181 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature