The parieto-occipital cortex is a candidate neural substrate for the human ability to approximate Bayesian inference.

ABSTRACT: Adaptive decision-making often requires one to infer unobservable states based on incomplete information. Bayesian logic prescribes that individuals should do so by estimating the posterior probability by integrating the prior probability with new information, but the neural basis of this integration is incompletely understood. We record fMRI during a task in which participants infer the posterior probability of a hidden state while we independently modulate the prior probability and likelihood of evidence regarding the state; the task incentivizes participants to make accurate inferences and dissociates expected value from posterior probability. Here we show that activation in a region of left parieto-occipital cortex independently tracks the subjective posterior probability, combining it

SUBMITTER: Singletary NM 

PROVIDER: S-EPMC10858241 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature