Coexistence of neuropathic corneal pain, corneal nerve abnormalities, depression, and low quality of life.

ABSTRACT:

Purpose

To evaluate the quality of life (QoL), mental health conditions and corneal morphology in neuropathic corneal pain (NCP) subjects without a significant ocular surface disease.

Methods

A composite questionnaire was administered to 228 consecutive subjects, assessing the pain intensity, duration, and quality using a modified version of the Self-Administered Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) and Pain Detect (PD) questionnaires. Subjects diagnosed with possible central NCP and two sub-groups of patients diagnosed with peripheral ocular pain completed an additional battery of mental health questionnaires and were examined by In Vivo Confocal Microscopy (IVCM).

Results

Of the 76 subjects that reported chronic ocular pain (duration >1 month

SUBMITTER: Leonardi A 

PROVIDER: S-EPMC10858266 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature