Determinants of survival following heart transplantation in adults with congenital heart disease.

ABSTRACT:

Background

Adult patients surviving with congenital heart disease (ACHD) is growing. We examine the factors associated with heart transplant outcomes in this challenging population with complex anatomy requiring redo-surgeries.

Methods

We reviewed the United Network for Organ Sharing-Standard Transplant Analysis and Research database and analyzed 35,952 heart transplants from January 1st, 2000, to September 30th, 2018. We compared transplant characteristics for ischemic cardiomyopathy (ICM) (n = 14,236), nonischemic cardiomyopathy (NICM) (n = 20,676), and ACHD (n = 1040). Mean follow-up was 6.20 ± 4.84 years. Kaplan-Meier survival curves and Cox-proportional hazards analysis were used to analyze survival data.

Results

Multivariable analysis confirmed that ACHD was ass

SUBMITTER: Sicim H 

PROVIDER: S-EPMC10858543 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature