Higher baseline heart rate variability in CCHS patients with progestin-associated recovery of hypercapnic ventilatory response.
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ABSTRACT:
SUBMITTER: Sevoz-Couche C
PROVIDER: S-EPMC10858557 | biostudies-literature | 2024 Feb
REPOSITORIES: biostudies-literature
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Higher baseline heart rate variability in CCHS patients with progestin-associated recovery of hypercapnic ventilatory response.
Sevoz-Couche Caroline C Patout Maxime M Charbit Beny B Similowski Thomas T Straus Christian C
Respiratory research 20240209 1
After a fortuitous observation of two cases of chemosensitivity recovery in women with congenital central hypoventilation syndrome (CCHS) who took desogestrel, we aimed to evaluate the ventilatory response to hypercapnia of five CCHS patients with or without treatment consisting of desogestrel (DESO) or levonorgestrel (LEVO). Only two patients became responsive to hypercapnia under treatment, according to their basal vagal heart rate variability. These results suggest that heart rate variability ...[more]
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