Systematic review of the patient burden of generalised myasthenia gravis in Europe, the Middle East, and Africa.

ABSTRACT:

Background

Myasthenia gravis (MG) is a rare autoimmune disease characterised by muscle weakness, and progression from ocular (oMG) to generalised (gMG) symptoms results in a substantial negative impact on quality of life (QoL). This systematic review aimed to provide an overview of the patient burden experienced by people living with gMG.

Methods

Electronic database searches (conducted March 2022), supplemented by interrogation of grey literature, were conducted to identify studies reporting patient burden outcomes in patients with gMG in Europe, the Middle East and Africa. Results were synthesised narratively due to the heterogeneity across trials.

Results

In total, 39 patient burden publications (representing 38 unique studies) were identified as relevant for inclus

SUBMITTER: McCallion J 

PROVIDER: S-EPMC10858594 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature