National survey of patient symptoms and therapies among 707 women with a lipedema phenotype in the United States.

ABSTRACT:

Background

National survey data exploring the patient experience with lipedema are lacking.

Methods

We conducted national surveys from 2016 to 2022 of women with lipedema as well as female controls. Surveys collected information on symptomatology, pain, and therapies. We performed logistic regression comparing symptoms among those with lipedema versus controls adjusting for age and BMI.

Results

A total of 707 women with lipedema and 216 controls completed the surveys. Those with lipedema had a mean age of 48.6 years and mean BMI of 40.9 kg/m². Lipedema symptom onset occurred frequently at puberty (48.0%) or pregnancy (41.2%). Compared to controls, women with lipedema were more likely to report leg swelling in heat (odds ratio [OR], 66.82; 95% CI, 33.04-135.

SUBMITTER: Aday AW 

PROVIDER: S-EPMC10858625 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature