Chronological improvement of survival in patients with advanced gastric cancer over 15 years.

ABSTRACT:

Background

Recent trials have reported a median overall survival (OS) of 11-17 months in patients with advanced gastric cancer (AGC). However, it is unclear how recently approved drugs contribute to patient prognosis.

Objectives

We aimed to evaluate the characteristics and survival in patients with AGC over the past 15 years.

Design

Retrospective study.

Methods

We evaluated data of 1355 patients with AGC who received first-line chemotherapy between January 2005 and March 2019 at a single institution. We compared the characteristics and survival rates across four periods: January 2005-December 2007 (period A), January 2008-February 2011 (period B), March 2011-May 2015 (period C), and June 2015-March 2019 (period D). The median follow-up duration was 13.1 months,

SUBMITTER: Ogata T 

PROVIDER: S-EPMC10858657 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature