How are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms?

ABSTRACT: Progress in mechanobiology allowed us to better understand the important role of mechanical forces in the regulation of biological processes. Space research in the field of life sciences clearly showed that gravity plays a crucial role in biological processes. The space environment offers the unique opportunity to carry out experiments without gravity, helping us not only to understand the effects of gravitational alterations on biological systems but also the mechanisms underlying mechanoperception and cell/tissue response to mechanical and gravitational stresses. Despite the progress made so far, for future space exploration programs it is necessary to increase our knowledge on the mechanotransduction processes as well as on the molecular mechanisms underlying microgravity-induced cell a

SUBMITTER: Davis T 

PROVIDER: S-EPMC10858953 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature