Antibacterial biofilm efficacy of calcium hydroxide loaded on Gum Arabic nanocarrier: an in-vitro study.

ABSTRACT:

Background

An innovative intracanal medication formulation was introduced in the current study to improve the calcium hydroxide (Ca(OH)₂) therapeutic capability against resistant Enterococcus faecalis (E. faecalis) biofilm. This in-vitro study aimed to prepare, characterize, and evaluate the antibacterial efficiency of Ca(OH)₂ loaded on Gum Arabic (GA) nanocarrier (Ca(OH)₂-GA NPs) and to compare this efficiency with conventional Ca(OH)₂, Ca(OH)₂ nanoparticles (NPs), GA, and GA NPs.

Materials and methods

The prepared nanoparticle formulations for the tested medications were characterized using Transmission Electron Microscope (TEM) and Fourier-Transform Infrared Spectroscopy (FTIR). 141 human mandibular premolars were sel

SUBMITTER: Mohamed AA 

PROVIDER: S-EPMC10859034 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature