Ontology highlight
ABSTRACT:
SUBMITTER: Wang L
PROVIDER: S-EPMC10859448 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Wang Luyao L Fan Yili Y Chen Boxiao B Zhang Jiawei J Yang Luyu L Qiu Xi X Jiang Huawei H Li Jinfan J Xiao Xibin X Huang Liansheng L Xu Yang Y
Frontiers in oncology 20240129
Despite significant improvements in prognosis, a subset of patients with primary central nervous system lymphoma (PCNSL) remains at high risk for relapse. The treatment of relapsed and refractory (R/R) PCNSL remains a major clinical challenge. Herein, we present a 24-year-old patient with PCNSL who relapsed 4 years after initial diagnosis and subsequently became refractory to high-dose methotrexate (HD-MTX), temozolomide, whole brain radiation therapy (WBRT), ibrutinib, and lenalidomide. She rec ...[more]