Prevalence and temporal trend of gastric preneoplastic lesions in Asia: A systematic review with meta-analysis.

ABSTRACT:

Background

Gastric cancer is the fifth most common cancer globally, with about 75% of cases occurring in Asia. While chronic atrophic gastritis (CAG) and intestinal metaplasia (IM) are well-recognized preneoplastic gastric lesions, we determined the prevalence and temporal trend of CAG and IM in Asia over the past 50 years.

Methods

In this systematic review and meta-analysis, we searched PubMed, Embase, MEDLINE, Scopus, and Web of Science for studies reporting the prevalence of CAG and IM in Asia (according to the United Nations geoscheme) published between 1970 and 2022. Heterogeneity was assessed by the I² index and Cochran Q test. We adopted the random effects model to estimate the pooled prevalence and 95% confidence interval (CI). The slope of prevalence was

SUBMITTER: Li Y 

PROVIDER: S-EPMC10859711 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature