Role of proton pump inhibitors dosage and duration in Helicobacter pylori eradication treatment: Results from the European Registry on H. pylori management.

ABSTRACT:

Background

Management of Helicobacter pylori (H. pylori) infection requires co-treatment with proton pump inhibitors (PPIs) and the use of antibiotics to achieve successful eradication.

Aim

To evaluate the role of dosage of PPIs and the duration of therapy in the effectiveness of H. pylori eradication treatments based on the 'European Registry on Helicobacter pylori management' (Hp-EuReg).

Methods

Hp-EuReg is a multicentre, prospective, non-interventionist, international registry on the routine clinical practice of H. pylori management by European gastroenterologists. All infected adult patients were systematically registered from 2013 to 2022.

Results

Overall, 36,579 patients from five countries with more than 1000 patients were analysed. Optimal (≥90%) first-

SUBMITTER: Pabon-Carrasco M 

PROVIDER: S-EPMC10859719 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature