Flow Cytometric Analysis for Identification of the Innate and Adaptive Immune Cells of Murine Lung.

ABSTRACT: The respiratory tract is in direct contact with the outside environment and requires a precisely regulated immune system to provide protection while suppressing unwanted reactions to environmental antigens. Lungs host several populations of innate and adaptive immune cells that provide immune surveillance but also mediate protective immune responses. These cells, which keep the healthy pulmonary immune system in balance, also participate in several pathological conditions such as asthma, infections, autoimmune diseases, and cancer. Selective expression of surface and intracellular proteins provides unique immunophenotypic properties to the immune cells of the lung. Consequently, flow cytometry has an instrumental role in the identification of such cell populations during steady-state and p

SUBMITTER: Christofides A 

PROVIDER: S-EPMC10859906 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature