PM₁₀ increases mortality risk in rheumatoid arthritis-associated interstitial lung disease.

ABSTRACT:

Objectives

The effect of air pollution on the prognosis of rheumatoid arthritis-associated interstitial lung disease (RA-ILD) remains poorly understood. We aimed to evaluate the effect of long-term exposure to particulate matter with an aerodynamic diameter of ≤10 µm (PM₁₀) and nitrogen dioxide (NO₂) on mortality in patients with RA-ILD.

Methods

We included 309 patients (mean age, 61.7 years; male, 44.3%) with RA-ILD. Individual-level long-term exposures to PM₁₀ and NO₂ at their residential addresses were estimated using a national-scale exposure prediction model. The effect of the two air pollutants on mortality was estimated using a Cox-proportional hazards model adjusted for individual-level and area-level characteristics.

Re

SUBMITTER: Kim SH 

PROVIDER: S-EPMC10860120 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature