The many faces of COPD in real life: a longitudinal analysis of the NOVELTY cohort.

ABSTRACT:

Background

The diagnosis of COPD requires the demonstration of non-fully reversible airflow limitation by spirometry in the appropriate clinical context. Yet, there are patients with symptoms and relevant exposures suggestive of COPD with either normal spirometry (pre-COPD) or preserved ratio but impaired spirometry (PRISm). Their prevalence, clinical characteristics and associated outcomes in a real-life setting are unclear.

Methods

To investigate them, we studied 3183 patients diagnosed with COPD by their attending physician included in the NOVELTY study (clinicaltrials.gov identifier NCT02760329), a global, 3-year, observational, real-life cohort that included patients recruited from both primary and specialist care clinics in 18 countries.

Results

We found that 1)

SUBMITTER: Agusti A 

PROVIDER: S-EPMC10860203 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature