Profile of cough triggers and their relationship with capsaicin cough sensitivity in chronic cough.

ABSTRACT:

Background

Cough hypersensitivity is an important part of the neurophysiology of cough, which presents with increased cough response to a lower level of stimuli or triggers. Classification of stimuli might bring about additional insight into the underlying mechanisms and management.

Objectives

This study investigated the profile of cough triggers in chronic cough patients and their relationship with capsaicin cough sensitivity.

Design

This was a cross-sectional observational study.

Methods

We enrolled patients with different causes of chronic cough from 2006 to 2021. Cough triggers were defined as cough response to chemical triggers, mechanical triggers, meal triggers, or thermal trigger. Cough sensitivity to capsaicin was evaluated by the capsaicin challenge t

SUBMITTER: Xu T 

PROVIDER: S-EPMC10860467 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature