Use of initial and subsequent antihypertensive combination treatment in the last decade: analysis of a large Italian database.

ABSTRACT:

Objective

The aim of the study was to assess the use of antihypertensive combination treatment, both as the initial and as a subsequent therapeutic step, in a large Italian population.

Methods

The residents of the Lombardy Region (Italy), aged 40 years or older, who were newly treated with antihypertensive drugs during 2012, 2015 and 2018 were identified and the drug treatment strategy (monotherapy and combination of two, three and more than three antihypertensive drugs) was assessed at treatment initiation, and after 6 months, 1, 2, and 3 years of treatment. Data were also analysed after stratification for demographic and clinical categories.

Results

About 100 000 patients were identified for each cohort. Monotherapy was the most common initial treatment strategy (75

SUBMITTER: Savare L 

PROVIDER: S-EPMC10860882 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature