Blood pressure response to standing is a strong determinant of masked hypertension in young to middle-age individuals.

ABSTRACT:

Objective

The pathophysiologic mechanisms of masked hypertension are still debated. The aim of this study was to investigate whether the blood pressure response to standing is a determinant of masked hypertension in young individuals.

Design and methods

We studied 1078 individuals (mean age 33.2 ± 8.5 years) with stage-1 untreated hypertension at baseline. Orthostatic response was defined as the difference between six SBP measurements in the orthostatic and supine postures. People with a response more than 6.5 mmHg (upper decile) were defined as hyperreactors. After 3 months of follow-up, 24-h ambulatory BP was measured and the participants were classified as normotensives (N = 120), white-coat hypertensive individuals (N = 168), masked hypertensive individuals (N = 166) and

SUBMITTER: Palatini P 

PROVIDER: S-EPMC10860891 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature