The impact of probiotics and vitamin C on the prevention of upper respiratory tract symptoms in two preschool children cohorts.

ABSTRACT:

Background/objectives

The efficacy of Lab4 probiotic and vitamin C combination on the prevention of upper respiratory tract infections (URTIs) was investigated in two studies with children. Our objective was to pool dataset of 57 preschool children from the PROCHILD study (ISRCTN28722693) and the dataset of 50 preschool matched cohort from the PROCHILD-2 study (ISRCTN26587549) to evaluate the impact of probiotic/vitamin C combination on the prevention of upper respiratory tract symptoms and provide a more robust assessment of effect using detailed individual level data.

Subjects/methods

The children were supplemented daily for 6 months with either the multistrain probiotic (1.25×10¹⁰ cfu/tablet consisting of two strains of Lactobacillus acidophilus CUL21 an

SUBMITTER: Paduchova Z 

PROVIDER: S-EPMC10861338 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature