Stereotactic Body and Conventional Radiotherapy for Painful Bone Metastases: A Systematic Review and Meta-Analysis.

ABSTRACT:

Importance

Conventional external beam radiotherapy (cEBRT) and stereotactic body radiotherapy (SBRT) are commonly used treatment options for relieving metastatic bone pain. The effectiveness of SBRT compared with cEBRT in pain relief has been a subject of debate, and conflicting results have been reported.

Objective

To compare the effectiveness associated with SBRT vs cEBRT for relieving metastatic bone pain.

Data sources

A structured search was performed in the PubMed, Embase, and Cochrane databases on June 5, 2023. Additionally, results were added from a new randomized clinical trial (RCT) and additional unpublished data from an already published RCT.

Study selection

Comparative studies reporting pain response after SBRT vs cEBRT in patients with painful bone

SUBMITTER: Bindels BJJ 

PROVIDER: S-EPMC10862159 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature