Rapid, systematic updating of movement by accumulated decision evidence.

ABSTRACT: Acting in the natural world requires not only deciding among multiple options but also converting decisions into motor commands. How the dynamics of decision formation influence the fine kinematics of response movement remains, however, poorly understood. Here we investigate how the accumulation of decision evidence shapes the response orienting trajectories in a task where freely-moving rats combine prior expectations and auditory information to select between two possible options. Response trajectories and their motor vigor are initially determined by the prior. Rats movements then incorporate sensory information as early as 60 ms after stimulus onset by accelerating or slowing depending on how much the stimulus supports their initial choice. When the stimulus evidence is in strong contr

SUBMITTER: Molano-Mazon M 

PROVIDER: S-EPMC10862760 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature