Sex differences in brain-behavior relationships in the first two years of life.

ABSTRACT:

Background

Evidence for sex differences in cognition in childhood is established, but less is known about the underlying neural mechanisms for these differences. Recent findings suggest the existence of brain-behavior relationship heterogeneities during infancy; however, it remains unclear whether sex underlies these heterogeneities during this critical period when sex-related behavioral differences arise.

Methods

A sample of 316 infants was included with resting-state functional magnetic resonance imaging scans at neonate (3 weeks), 1, and 2 years of age. We used multiple linear regression to test interactions between sex and resting-state functional connectivity on behavioral scores of working memory, inhibitory self-control, intelligence, and anxiety collected at 4 years

SUBMITTER: Fenske SJ 

PROVIDER: S-EPMC10862872 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature