Secondary peripheral chondrosarcoma in multiple osteochondromas: a retrospective single-institution case series.

ABSTRACT:

Background

Multiple osteochondromas is genetic disorder characterized by the formation of multiple benign cartilage-capped bone tumors, named osteochondromas, during skeletal development. The most feared complication is the secondary peripheral chondrosarcoma, a malignant cartilaginous neoplasm that arises from the chondroid cap of pre-existent osteochondromas. We conducted a retrospective cohort study on patients diagnosed and followed up from 1960 to 2019 to describe the clinical and pathological features of individuals affected by peripheral chondrosarcoma in multiple osteochondromas, to evaluate follow up information and individual outcome and to compare the results with literature. Data, including age, gender, site, histological grade, cartilage cap thickness, surgical treatme

SUBMITTER: Gnoli M 

PROVIDER: S-EPMC10863250 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature