Nanomagnetic CoFe₂O₄@SiO₂-EA-H₃PO₄ as a zwitterionic catalyst for the synthesis of bioactive pyrazolopyranopyrimidines and dihydropyrano[2,3-c]pyrazoles.

ABSTRACT: This study presents the development of a phosphoric acid-based zwitterionic catalyst immobilized on CoFe₂O₄ nanoparticles [CoFe₂O₄@SiO₂-EA-H₃PO₄]. The structure of the nanocatalyst CoFe₂O₄@SiO₂-EA-H₃PO₄ was identified by applying several spectroscopic techniques, i.e. FT-IR, SEM, TEM, XRD, EDX, elemental Mapping, VSM, TGA, and BET techniques. The catalytic efficiency of CoFe₂O₄@SiO₂-EA-H₃PO₄ was evaluated in the water-based multicomponent synthesis of pyrazolopyranopyrimidine and dihydropyrano[2,3-c]pyrazole derivatives. Subsequently, an exploration of the antibacterial properties of the comp

SUBMITTER: Mirzaie A 

PROVIDER: S-EPMC10863708 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature