Prognostic Value of Nighttime Double Product in Nondialysis Chronic Kidney Disease With Hypertension.

ABSTRACT:

Background

Both nighttime systolic blood pressure and pulse rate are associated with adverse outcomes in patients with chronic kidney disease (CKD). However, nighttime double product (DP), which is the product of nighttime systolic blood pressure and pulse rate, has not yet been investigated in this context. The present study aimed to explore the prognostic value of nighttime DP for adverse outcomes in patients with CKD and hypertension.

Methods and results

This retrospective cohort study included a total of 1434 patients with nondialysis CKD complicated by hypertension. The patients were enrolled in Zhuhai and Guangzhou, China, with a median follow-up of 23.8 months. Patient enrollment for the high or low nighttime DP group was performed on the basis of the cutoff value det

SUBMITTER: Jiang X 

PROVIDER: S-EPMC10863753 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature