Management of repository corticotropin injection therapy for non-infectious uveitis: a Delphi study.

ABSTRACT:

Purpose

Diagnosis and management of non-infectious uveitis (NIU), a major cause of blindness worldwide, are challenging. Corticosteroids, the cornerstone of therapy, are not appropriate for long-term use, and while non-biologic and biologic immunomodulators may be used for some patients, data on their efficacy and safety in this population are limited. Repository corticotropin injection (RCI), believed to affect uveitis by multiple mechanisms, has received regulatory approval for treatment of ophthalmic diseases including posterior uveitis, but is not widely used or discussed in guidelines for the management of uveitis and ocular inflammatory diseases.

Methods

The index study employed a modified Delphi process with a panel of 14 US-based ophthalmologists. Consensus recommend

SUBMITTER: Nguyen QD 

PROVIDER: S-EPMC10863995 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature