Dataset Information

Diagnostic Performance Using a Combination of MRI Findings for Evaluating Cognitive Decline.

ABSTRACT:

Purpose

We investigated potentially promising imaging findings and their combinations in the evaluation of cognitive decline.

Materials and methods

This retrospective study included 138 patients with subjective cognitive impairments, who underwent brain MRI. We classified the same group of patients into Alzheimer's disease (AD) and non-AD groups, based on the neuropsychiatric evaluation. We analyzed imaging findings, including white matter hyperintensity (WMH) and cerebral microbleeds (CMBs), using the Kruskal-Wallis test for group comparison, and receiver operating characteristic (ROC) curve analysis for assessing the diagnostic performance of imaging findings.

Results

CMBs in the lobar or deep locations demonstrated higher prevalence in the patients with AD compared to those in the non-AD group. The presence of lobar CMBs combined with periventricular WMH (area under the ROC curve [AUC] = 0.702 [95% confidence interval: 0.599-0.806], p < 0.001) showed the highest performance in differentiation of AD from non-AD group.

Conclusion

Combinations of imaging findings can serve as useful additive diagnostic tools in the assessment of cognitive decline.

SUBMITTER: Byun JY

PROVIDER: S-EPMC10864162 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature

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Publications

Diagnostic Performance Using a Combination of MRI Findings for Evaluating Cognitive Decline.

Byun Jin Young JY Lee Min Kyoung MK Jung So Lyung SL

Journal of the Korean Society of Radiology 20231209 1

<h4>Purpose</h4>We investigated potentially promising imaging findings and their combinations in the evaluation of cognitive decline.<h4>Materials and methods</h4>This retrospective study included 138 patients with subjective cognitive impairments, who underwent brain MRI. We classified the same group of patients into Alzheimer's disease (AD) and non-AD groups, based on the neuropsychiatric evaluation. We analyzed imaging findings, including white matter hyperintensity (WMH) and cerebral microbl ...[more]

PMID: 38362402

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Dataset Information

Diagnostic Performance Using a Combination of MRI Findings for Evaluating Cognitive Decline.

Purpose

Materials and methods

Results

Conclusion

Publications

Diagnostic Performance Using a Combination of MRI Findings for Evaluating Cognitive Decline.

Similar Datasets

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