Neuromorphic electro-stimulation based on atomically thin semiconductor for damage-free inflammation inhibition.

ABSTRACT: Inflammation, caused by accumulation of inflammatory cytokines from immunocytes, is prevalent in a variety of diseases. Electro-stimulation emerges as a promising candidate for inflammatory inhibition. Although electroacupuncture is free from surgical injury, it faces the challenges of imprecise pathways/current spikes, and insufficiently defined mechanisms, while non-optimal pathway or spike would require high current amplitude, which makes electro-stimulation usually accompanied by damage and complications. Here, we propose a neuromorphic electro-stimulation based on atomically thin semiconductor floating-gate memory interdigital circuit. Direct stimulation is achieved by wrapping sympathetic chain with flexible electrodes and floating-gate memory are programmable to fire bionic spikes,

SUBMITTER: Bao R 

PROVIDER: S-EPMC10864345 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature