Radical pair model for magnetic field effects on NMDA receptor activity.

ABSTRACT: The N-methyl-D-aspartate receptor is a prominent player in brain development and functioning. Perturbations to its functioning through external stimuli like magnetic fields can potentially affect the brain in numerous ways. Various studies have shown that magnetic fields of varying strengths affect these receptors. We propose that the radical pair mechanism, a quantum mechanical process, could explain some of these field effects. Radicals of the form [Formula: see text], where R is a protein residue that can be Serine or Tyrosine, are considered for this study. The variation in the singlet fractional yield of the radical pairs, as a function of magnetic field strength, is calculated to understand how the magnetic field affects the products of the radical pair reactions. Based on the result

SUBMITTER: Nair PS 

PROVIDER: S-EPMC10864372 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature