Poor serum uric acid control increases risk for developing hypertension: a retrospective cohort study in China.

ABSTRACT:

Background

Serum uric acid (SUA) has been suggested as a contributor of hypertension. However, reports on the relationship between changes in SUA and hypertension are limited. Hence, we aimed to investigate the potential impact of SUA, especially its change over time, on hypertension incidence.

Methods

This dynamic cohort included 6052 participants without hypertension at baseline. Participants were categorized into six grades based on whether baseline SUA was high and whether changes in SUA progressed to hyperuricemia or decreased to normal levels. Grades 1 to 6 represented the participants' SUA control from best to worst. Logistic regression and restricted cubic spline (RCS) models were used to explore the association of the grades of SUA control and hypertension incidence

SUBMITTER: Lin Z 

PROVIDER: S-EPMC10864606 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature