Safety and immunogenicity of different booster vaccination schemes for COVID-19 used in El Salvador.

ABSTRACT:

Purpose

The effectiveness of coronavirus disease 2019 (COVID-19) vaccination schemes and the combination of vaccines of various platforms for administering booster doses is still being studied since it will depend on the population's response to vaccines. We aimed to evaluate the safety, protection, and immunogenicity of the Salvadorean population's third dose booster COVID-19 vaccine and the potential benefit of homologous vs. heterologous regimens.

Materials and methods

This is an analytical observational cohort study in a population aged 18 to 65 years that was primarily vaccinated with AstraZeneca, Sinovac, or Pfizer/BioNTech. Volunteers were recruited (n=223) and followed up for 3 months after receiving the 3rd vaccine (BNT162b2) as a booster. Adverse reactions were mon

SUBMITTER: Sandoval X 

PROVIDER: S-EPMC10864880 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature