Bayesian estimation in NONMEM.

ABSTRACT: Bayesian estimation is a powerful but underutilized tool for answering drug development questions. In this tutorial, the principles of Bayesian model development, assessment, and prior selection will be outlined. An example pharmacokinetic (PK) model will be used to demonstrate the implementation of Bayesian modeling using the nonlinear mixed-effects modeling software NONMEM.

SUBMITTER: Johnston CK 

PROVIDER: S-EPMC10864934 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature