Safety and Efficacy of Midline vs Peripherally Inserted Central Catheters Among Adults Receiving IV Therapy: A Randomized Clinical Trial.

ABSTRACT:

Importance

Midline catheters (MCs) are widely used, but safety and efficacy compared with peripherally inserted central catheters (PICCs) has not been adequately evaluated.

Objective

To compare the safety and efficacy of MCs with PICCs among adult patients with an anticipated intravenous therapy lasting from 5 to 28 days.

Design, setting, and participants

This parallel, 2-group, open-label, randomized clinical trial (RCT) was conducted in Denmark from October 2018 to February 2022 at a single academic tertiary care center. Adult inpatients and outpatients were consecutively randomized.

Intervention

Patients were randomized in a 1:1 ratio to either the MC group or the PICC control group.

Main outcomes and measures

The primary outcome was catheter-related

SUBMITTER: Thomsen SL 

PROVIDER: S-EPMC10865154 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature