Opportunities for Pharmacogenetic Testing to Guide Dosing of Medications in Youths With Medicaid.

ABSTRACT:

Importance

There are an increasing number of medications with a high level of evidence for pharmacogenetic-guided dosing (PGx drugs). Knowledge of the prevalence of dispensings of PGx drugs and their associated genes may allow hospitals and clinical laboratories to determine which pharmacogenetic tests to implement.

Objectives

To investigate the prevalence of outpatient dispensings of PGx drugs among Medicaid-insured youths, determine genes most frequently associated with PGx drug dispenses, and describe characteristics of youths who were dispensed at least 1 PGx drug.

Design, setting, and participants

This serial cross-sectional study includes data from 2011 to 2019 among youths aged 0 to 17 years in the Marketscan Medicaid database. Data were analyzed from August to

SUBMITTER: Tang Girdwood S 

PROVIDER: S-EPMC10865156 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature