Effectiveness of a thrombin-gelatin flowable for treating severe liver bleeding: an experimental study.

ABSTRACT:

Background

Current scientific evidence has pointed out the relevance of hemostatic products for improving clinical outcomes in liver trauma, including increased survival rates and reductions in bleeding-related complications. The purpose of this study was to compare the use of the gelatin-thrombin flowable (Flowable) versus the standard technique of Packing in a new experimental liver injury model.

Methods

Twenty-four swine were prospectively randomized to receive either Flowable or standard packing technique. We used a novel severe liver injury model, in which the middle and left suprahepatic veins were selectively injured, causing an exsanguinating hemorrhage. The main outcome measure was the percentage of lost blood volume.

Results

The median total percentage of to

SUBMITTER: Sanchez-Del-Valle FJ 

PROVIDER: S-EPMC10865537 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature