Whole-genome resequencing provides insights into the diversity and adaptation to desert environment in Xinjiang Mongolian cattle.

ABSTRACT:

Background

Xinjiang Mongolian cattle is an indigenous breed that inhabits the Taklimakan Desert and is characterized by its small body size. However, the genomic diversity, origin, and genetic basis underlying the adaptation to the desert environment have been poorly studied.

Results

We analyzed patterns of Xinjiang Mongolian cattle genetic variation by sequencing 20 genomes together with seven previously sequenced genomes and comparing them to the 134 genomes of nine representative breeds worldwide. Among the breeds of Bos taurus, we found the highest nucleotide diversity (0.0024) associated with the lower inbreeding coefficient (2.0110^-6), the lowest linkage disequilibrium (r² = 0.3889 at distance of 10 kb), and the highest effective population size (

SUBMITTER: Xu L 

PROVIDER: S-EPMC10865613 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature